Home >> News

How much do you know about Pharmaceutical Intermediates?

Jan. 14, 2020

Pharmaceutical Intermediates are actually some chemical raw materials or chemical products used in the pharmaceutical synthesis process. This chemical product does not require a production license for drugs and can be produced in an ordinary chemical plant. As long as it reaches a certain level, it can be used for the synthesis of drugs. As a Pharmaceutical Intermediates Supplier, share with you.

China needs about 2,000 kinds of raw materials and intermediates supporting the chemical industry each year, and the demand is over 2.5 million tons. After more than 30 years of development, chemical raw materials and intermediates required for the production of pharmaceuticals in China can be basically matched, and only a small part needs to be imported. Moreover, due to China's abundant resources and low raw material prices, many intermediates have been exported in large quantities. So, what development opportunities does China's pharmaceutical intermediates field face?

Sodium Periodate

Sodium Periodate


The first is that the production enterprises are mostly private enterprises, with flexible operations and small investment scales, basically ranging from several million to 10 million yuan. The second is that the production enterprises are relatively geographically distributed, mainly in Zhejiang Taizhou and Jiangsu Jinzhou. The area is centered on the altar; the third is that with the country's increasing attention to environmental protection issues, the pressure on manufacturing enterprises to build environmental protection processing facilities has increased; the fourth is the rapid update of products. After a product is generally available on the market for 3 to 5 years, its profit margin drops sharply. This forces companies to continuously develop new products or improve their production processes in order to maintain high production profits. Fifth, high production profits of pharmaceutical intermediates For chemical products, the production process of the two is basically the same, so more and smaller chemical companies have joined the ranks of producing pharmaceutical intermediates, resulting in increasingly fierce disorderly competition in the industry; Sixth, compared with APIs, production The profit margin of intermediates is low, and the production process of APIs and pharmaceutical intermediates is similar. Therefore, some companies have not only produced intermediates but have also used their own advantages to start the production of APIs.

Sodium Periodate is the sodium salt of periodic acid. It has two forms, sodium meta periodate (chemical formula: NaIO4) and sodium periodate (chemical formula: Na5IO6), which can be used as oxidants in organic synthesis.

Sodium periodate is the main raw material of the pharmaceutical industry and is also used as an oxidant for the food industry, general analytical reagents and chromatographic analysis reagents.

Aqueous solutions of sodium meta periodate, potassium meta periodate, and periodic acid can oxidize fluorene glycol, o-polyols, α-hydroxy acids, α-diketones, α-amino ketones, 1-amino-2-hydroxyl Compounds that break carbon-carbon bonds to form the corresponding carbonyl compounds, aldehydes and ketones. The reaction is quantitative and can be used to infer the structure of the reactants.

skype whatsapp E-mail